Preimplantation Genetic Testing for Monogenic disorders, PGT-M (formerly PGD) is an early genetic diagnostic test for embryos produced during IVF, prior to their transfer to the uterus.

Preimplantation Genetic Testing for Monogenic disorders, PGT-M involves the biopsy of embryos to help embryo selection based on information obtained following genetic testing. One would need to undergo ovarian stimulation to retrieve eggs from the ovaries. These are then used to create embryos with the help of sperm. Five days later, embryos that reach the blastocyst stage are biopsied and cryopreserved. The genetic material is then sent for testing to a specialised laboratory. It can take 3-4 weeks to get the results. An embryo that is free of disease is then transferred into the womb in a subsequent cycle.


Who should perform PGT-M test?

PGT-M is indicated for couples with personal or familial high-risk for single gene conditions including Cystic Fibrosis, Fragile-X syndrome, Muscular dystrophy, Huntington’s disease, and others.

PGT-M | Preimplantation Genetic Testing - Monosomy | Embryo Biopsy (3:00)



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