This test includes a complimentary call with our fertility expert, Dr Irfana Koita.
A sperm cell has the vital task of carrying genetic data to the egg cell. Damage to the sperm cell’s DNA structure may interfere with its ability to properly fertilise an egg cell and help it develop into a healthy, thriving embryo.
Through this sperm DNA fragmentation test, you’ll receive information vital in preventing specific issues like underdevelopment of the embryo or miscarriage.
The Sperm Chromatin Dispersion (SCD) test is a diagnostic technique to assess sperm DNA fragmentation (SDF). It works by treating sperm with an acid to denature the DNA, followed by lysis to remove proteins. Sperm with intact DNA form large halos of chromatin dispersion, while fragmented DNA results in small or no halos. This test is simple, cost-effective, and widely used in fertility evaluations. This test is performed at our clinic in Enfield.
The COMET assay (EXACT test) is another method for detecting DNA damage in sperm. In this test, sperm cells are embedded in agarose gel, lysed, and subjected to electrophoresis. Fragmented DNA migrates, forming a "comet tail," with the length and intensity of the tail indicating the degree of DNA damage. The Comet assay provides detailed quantitative and qualitative information on sperm DNA integrity. This test is performed at our clinic in Harley Street. (If you are looking for the EXTEND test, please get in touch. We can arrange this test as well.)
You’ll have to visit our London clinic to maintain the sample's integrity. Book your preferred date through our secure online portal and read the prerequisites for your sperm test below.
Your results will be reviewed by our in-house fertility expert, Dr Irfana Koita, who’ll discuss your results and explore possible treatment options if required.
Feel free to use our services or contact us, even if you’re undergoing treatment at another private or NHS Clinic.